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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
22.73
Human Site:
Y725
Identified Species:
33.33
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
Y725
T
F
H
A
F
N
K
Y
K
R
E
G
F
C
L
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
Y817
T
F
H
A
F
N
K
Y
K
R
E
G
F
C
L
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
Y977
T
F
H
A
F
N
K
Y
K
R
E
G
F
C
L
Dog
Lupus familis
XP_547953
806
90703
Y732
T
F
H
A
F
N
K
Y
K
R
E
G
F
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
G701
S
G
P
A
V
R
S
G
L
N
A
T
F
M
A
Rat
Rattus norvegicus
Q63531
735
82865
M655
A
K
D
L
V
S
K
M
L
H
V
D
P
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
Y642
T
F
H
A
F
N
K
Y
K
R
E
G
F
C
L
Chicken
Gallus gallus
Q5F3L1
789
89022
Y715
T
F
H
A
F
N
K
Y
K
R
E
G
F
C
L
Frog
Xenopus laevis
P10665
733
82620
K660
M
L
H
V
D
P
H
K
R
L
T
A
K
Q
V
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
L672
R
Y
T
A
E
Q
V
L
K
H
S
W
I
A
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
Q924
G
G
M
F
D
D
Q
Q
Q
L
E
F
M
H
D
Honey Bee
Apis mellifera
XP_395099
910
102507
R744
G
A
R
L
A
Q
R
R
K
L
H
K
R
S
T
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
G691
F
L
H
A
N
R
D
G
F
H
L
L
D
V
A
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
Q685
M
R
A
F
H
T
A
Q
R
E
G
F
L
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
E404
A
I
N
W
K
K
L
E
A
R
E
V
Q
P
S
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
K610
S
W
K
K
L
L
L
K
G
Y
I
P
P
Y
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
13.3
6.6
N.A.
100
100
6.6
13.3
N.A.
6.6
6.6
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
20
13.3
N.A.
100
100
20
20
N.A.
26.6
13.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
7
7
57
7
0
7
0
7
0
7
7
0
7
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
38
7
% C
% Asp:
0
0
7
0
13
7
7
0
0
0
0
7
7
0
7
% D
% Glu:
0
0
0
0
7
0
0
7
0
7
50
0
0
0
0
% E
% Phe:
7
38
0
13
38
0
0
0
7
0
0
13
44
0
0
% F
% Gly:
13
13
0
0
0
0
0
13
7
0
7
38
0
0
0
% G
% His:
0
0
50
0
7
0
7
0
0
19
7
0
0
13
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
7
0
7
0
0
% I
% Lys:
0
7
7
7
7
7
44
13
50
0
0
7
7
0
7
% K
% Leu:
0
13
0
13
7
7
13
7
13
19
7
7
7
7
38
% L
% Met:
13
0
7
0
0
0
0
7
0
0
0
0
7
7
0
% M
% Asn:
0
0
7
0
7
38
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
7
0
0
0
0
0
7
13
7
0
% P
% Gln:
0
0
0
0
0
13
7
13
7
0
0
0
7
7
7
% Q
% Arg:
7
7
7
0
0
13
7
7
13
44
0
0
7
0
0
% R
% Ser:
13
0
0
0
0
7
7
0
0
0
7
0
0
7
7
% S
% Thr:
38
0
7
0
0
7
0
0
0
0
7
7
0
0
13
% T
% Val:
0
0
0
7
13
0
7
0
0
0
7
7
0
7
7
% V
% Trp:
0
7
0
7
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
38
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _